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As of 2024, around one in 2,875 babies born in the United States had spina bifida without anencephaly. Spina bifida, anencephaly, and encephalocele are neural tube defects in which the neural tube does not close properly, often resulting in damage to the spinal cord and nerves. This statistic shows the number of live births per one case of select brain/spine birth defects in the United States as of 2024.